PReS-FINAL-1009: Antioxidant superoxide dismutase activity is paradoxically normal in juvenile systemic lupus erythematosus
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چکیده
منابع مشابه
PReS-FINAL-1009: Antioxidant superoxide dismutase activity is paradoxically normal in juvenile systemic lupus erythematosus
Introduction Damage via generation of free radicals has been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Numerous studies demonstrate both direct and surrogate evidence for a high burden of oxidative and nitrative stress which parallels disease activity. Antioxidants such as superoxide dismutase (SOD) function to protect against oxidative damage by neutralizing free ra...
متن کاملPReS-FINAL-2300: Shrinking lung syndrome in an adolescent male with juvenile systemic lupus erythematosus
Introduction Pulmonary involvement occurs in up to 80% of Systemic Lupus Erythematosus (SLE) patients, with decreased diffusing capacity (DLCO) and interstitial lung disease being most common. Shrinking lung syndrome (SLS) is a rare complication, which consists in small lung volumes, elevation of the diaphragm and restrictive physiology without parenchymal or pleural involvement. Its pathogenes...
متن کاملPReS-FINAL-2294: Juvenile systemic lupus erythematosus in ethnically homogeneous population: a single-centre experience
Methods Electronic records of patients attending the Unit over the period from January 2005 (when hospital information system was established) to April 2012 were reviewed. Inclusion criteria were diagnosis of SLE according to the modified ACR classification criteria in patients aged ≤18 years and active disease requiring daily steroid dose higher than 5 mg. Data on clinical and laboratory findi...
متن کاملPReS-FINAL-2302: Evaluation of magnetic resonance imaging abnormalities in juvenile neuro-psychiatric systemic lupus erythematosus
Introduction Neuropsychiatric systemic lupus erythematosus (NPSLE) is a diagnostically challenging, severe, and life-threatening condition. Neuroimaging techniques such as magnetic resonance imaging (MRI) are increasingly used to assist the diagnosis and monitoring of the disease course in adults with NPSLE. The role of MRI in the evaluation of children and adolescents with suspected juvenile N...
متن کاملPReS-FINAL-2352: Apoptosis profile in patients with juvenile-onset systemic lupus erythematosus
Methods Forty-three JSLE patients (revised ACR criteria, mean age = 14.3 yrs, 36F:7M), and 35 age and gender matched healthy controls were studied; 30 JSLE had SLEDAI score 4, reflected active disease. Soluble molecules were measured by commercial ELISA kits. Lymphocytes and monocytes were stained with specific moAbs and analyzed by flow cytometry. Kruskal-Wallis test and Spearman’s rank were e...
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2013
ISSN: 1546-0096
DOI: 10.1186/1546-0096-11-s2-p7